Nerves and Intestinal Mast Cells Modulate Responses to Enterotoxins.

نویسندگان

  • Charalabos Pothoulakis
  • Ignazio Castagliuolo
  • J. Thomas LaMont
چکیده

Experiments in intact animals exposed to enterotoxins demonstrate that neurons and immune cells of the lamina propria regulate toxin-induced diarrhea and tissue damage. Clostridium difficile toxins cause profound diarrhea and acute inflammation by activating a complex cascade initiated by toxin binding to enterocyte receptors.

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عنوان ژورنال:
  • News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

دوره 13  شماره 

صفحات  -

تاریخ انتشار 1998